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Issues-Based
Framework for Bio 101
from the report of the
National Life Science Education Conference
II, Coalition for Education in
the Life Sciences, February 21-23, 1992
Introduction
Inherent in the recommendations urged in this
report is the overall belief that science,
especially the life sciences, must be part of a
core of knowledge for all Americans if they are
to participate fully in our society. There is
much about the natural work that we do not know,
yet much that we need to know. We live in a
complex world, besieged by complex problems. Our
ability to understand, and appropriately respond
to the issues of the day, relies on the
supposition that we, as a people, are educated
regarding these issues. All too often that is not
the case. The situation is urgent, and growing
worse with each passing day.
Participants at the second meeting of the
Coalition for Education in the Life Sciences
(CELS II) devised the following Guiding
Principles as a way to correct the current state
of affairs, and move us toward the educated state
necessary to our survival as a world and as a
people.
Guiding principles
The recommendations below are not a placebo,
nor are they a coat of paint thrown over a badly
dilapidated educational structure. They are the
ingredients vital to a necessary overhaul of our
entire system of science education. They
represent, in short, our best hope to provide a
means to achieve literacy in the life sciences in
this country.
 Conducting
investigative biology for non-science
majors in a large lecture setting can
pose a special challenge. To overcome it,
Dr. Ruth Beattie, an assistant professor
of Biology at the University of Kentucky
(Lexington, Ky.), designed an in-class
exploration in which students analyze
soil samples collected from around the
state.
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1. Science should form a core
consisting of 20 percent of the undergraduate
curricula. Since this must build upon the
education students receive in the K-12 years, we
applaud all efforts to develop and implement
hands-on, inquiry-driven science education for
these students.
2. To become educated citizens, all college
and university students need no less than a
year's study of the biological sciences,
including an inquiry-driven lab and/or field
experience relating to the critical issues of our
times.
3. Given this need, new thinking must occur,
and new resources must be developed, including
endowed chairs, adequate provisions for support
staff, and grants for curriculum development at
the college and university level.
4. Mechanisms must be developed to foster
closer interactions between teachers/ science
educators, researchers, and college/university
faculty to maintain a close collab-oration in
this endeavor.
The urgency of these goals must be understood
by our university administrators and faculty,
scientists, parents, and students alike. Further,
they must be taken to heart by legislators,
business leaders, and other decision makers,
including the future electorate, who must have
the ability to deal with complex issues and make
informed decisions.
 At Louisiana Tech
University (Ruston, La.), faculty from
biology, education and math co-direct a
year-long interdisciplinary science
course specifically designed for
elementary education majors. Closely
aligned with a revised science methods
course, this interdisciplinary course
features an investigative, inquiry-based
approach.
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CELS, and the many scientific
societies it represents, will work to advocate
the policy changes necessary to implement these
recommendations. Further, it will work to
facilitate communication between the educational
forums of the National Academy of Sciences and
other groups, federal and private funding
agencies, and through the members of our
professional societies, who are active
participants in research, education and industry.
Inherent to science and science education is
the perspective through which science must be
understood and conducted. Science is the sum of
the efforts to understand the natural world in a
systematic, empirical manner. An experimental
approach is based on observations to construct
models of phenomena, events, and structures that
allow prediction. Science values the power of
theory for explaining and predicting. Science is
dynamic and ever-changing. Science is
problem-solving. It is similar to detective work,
involving investigation, and it is fun. The
underlying assumption is that there are patterns
to be discovered. Science is a community effort
and is self-correcting. Success of science
depends upon integrity, honesty, openness,
logical thought, care and precision. It is driven
by curiosity and skepticism. The scientific study
of life involves responsible investigation of all
life forms.
Issues
Life science issues cry out from the headlines
of newspapers daily. These issues affect much of
what we do, and the very quality of our lives.
How they are resolved will determine our future
and survival as a world and as a people.
Comprehension of and solutions to these issues
are inherently based through the understanding of
the life sciences.
Thus, systemic reform in life sciences
education begins with an analysis of what
knowledge students must possess to deal with the
problems confronting us, and to be educated about
the world around and within us. A consensus on
what it is students must know forms the
foundation for creating a more effective
curriculum and methods of delivery.
Representatives from 30 life science societies
present at CELS II selected six over-arching
issues that help to define life science and its
relationship to society as a whole. They assert
that, at a minimum, these issues listed below,
must be studied in order to produce educated and
contributing members of society. These issues do
not represent a comprehensive list, but are
indicative of the scope and type of concepts and
concerns that need to be covered in undergraduate
life science education.
(It should be noted that use of the words
"we" and "our" in the issues
described below encompass not only humans, but
all forms of plant, animal, and microbial life.)
1. Wellness
Balance/homeostasis. Our bodies are
constructed with interrelated systems that
respond to change and maintain balance.
Nutrition/energy. Proper nutrition
provides the building blocks and sources of
energy to maintain the balance of our systems.
Growth and development. We are designed
to live, grow, reproduce, and die.
Disease/pathogenicity. We live in
competition with a number of chemicals, viruses,
microbes, and other organisms that can disrupt
our balance in different ways.
Protection/immunity. We have evolved
defenses against pathogens, and these defenses
can be strengthened by manipulation.
Community health. Our social
institutions must be designed to protect the
health of individuals, providing, clean water,
adequate nutrition, and access to medical
services.
2. Shaping/Reshaping Life
Inheritance. (Mendelian and
non-Mendelian). Living organisms are governed by
a set of inherited instructions that are passed
on from one generation to the next.
Information read-out. (normal gene
expression, genetics of development). Information
encoded in the structure of DNA is expressed by
the cell as proteins which shape the traits of
the cell and the organism. Expression of traits
is influenced by environment.
Variability/evolution. (diversity). All
organisms share a common genetic origin. Changes
in genetic information occur and may result in
changes in traits that affect the interaction of
the individual with the environment.
Sexual reproduction. Mixing the encoded
information (DNA) through the process of sexual
reproduction has resulted in an evolving
diversity of organisms.
Gene manipulation. Humans now have the
ability to alter this information and quickly
change specific attributes of living organisms.

Dr. Jill Manske (right) of
the Biology Department at the University
of St. Thomas (St. Paul, Minn.) and Erin
Sullivan, her summer research student,
discuss the results of Erins
honors thesis project. The research
was supported by a summer fellowship
grant from the Council on Undergraduate
Research.
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3. Overpopulation
Carrying capacity/exponential growth.
The human species has continued to grow
exponentially and is challenging the resources of
the earth.
Primary productivity. Humans are
dependent upon the primary productivity of other
species.
Limiting factors. There are physical,
chemical, and biotic factors that limit primary
productivity.
Interconnectedness. Due to the
interconnectedness of the living and non-living
components of the earth, population growth
impacts every aspect of the earth's systems.
Reproductive biology. Understanding of
fundamental concepts about reproductive biology
at organismal and population levels is essential
to understanding the consequences of
overpopulation.
Cultural factors. Powerful determinants
in the rate of human reproduction are
socioeconomic status, religion, education, and
the status of women.
4. Resource Utilization
Resources. Important resources for life
on earth include food, water, air, space to live,
shelter; humans also demand energy.
Renewable resources. Biological systems
have the capacity to renew some of the resources
we use. Humans must be careful to maintain that
capacity.
Non-renewable resources. Rapid
utilization of non-renewable resources reduces
their availability for future generations. We
must investigate ways to reduce the rate of such
utilization and consider the use of alternate
resources.
Interconnectedness. Tampering with
certain resources (e.g., soil, air, water)
affects the availability of other resources
(e.g., plants).
 Dr. Anne Houde,
Department of Biology, Lake Forest
College (Lake Forest, Ill.), emphasizes
the creativity of science by having
students develop their skills in
observing patterns, asking questions,
generating hypotheses and testing
predictions. Undergraduate students Sam
Weinert (left) and Chris Baker engage in
field investigations as part of her
ecology course.
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5. Alteration of Natural
Systems
Ecosystems. The living world is a
closed system that has cycles of energy transfer
and matter flow.
Biodiversity. The world's biodiversity
is rapidly disappearing. Biodiversity is the
variety of life at all levels of biology. Not
only does biodiversity enhance the quality of our
lives aesthetically and practically, it is part
of our life-support system.
Changes have consequences. (interactions
and interdependence). Change is a part of natural
systems. Physical and biological changes in the
world affect each other. Human activities have
increased the rate of change with sometimes
devastating effects on natural systems.
Adaptation/extinction. These processes
are the result of biological evolution in an
ever-changing environment as evidenced by
history.
Humans as part of the system. Humans,
as organisms, are intimately linked with the
natural world. Humans have the ability to impact
natural systems beyond their immediate
environment in time and space. However,
ultimately there are consequences for living on
limited resources.
6. Functional/Dysfunctional Behavior
(Inter-organismal interaction)
Individuals in relation to their
environment. Organisms detect, respond, and
compete for resources in their physical and
biological environment.
Individuals in relation to other species.
Organisms interact with other organisms in
fundamental ways. Types of relationships include
competition, predation, and mutualism.
Individuals in relation to conspecifics.
Behavior often occurs in a social context.
Types of social behavior include communication,
competition, and cooperation.
Determinants of behavior. Behavior can
be understood at different levels. There are
chemical, neural, morphogenic, and cultural
determinants of behavior. Behavior has both
learned and innate components which have evolved
over generations.
Dysfunctional behaviors (substance
abuse, social conflict). This behavior often
occurs under stress.
 Dr. Carol Budd,
Coordinator of Freshman Laboratories at
St. Lawrence University (Canton, N.Y.),
helps students acquire basic laboratory
skills and then put them to use in
independent projects that culminate in
formal scientific presentations. Pictured
are undergraduate students Jennifer
Kunzelman (left) and Carrie Miller.
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